• Compensating for deleterious mutations

    Updated: 2011-07-31 15:00:33
    Home About People Resources Meetings courses The Evolution Medicine Review bridging the gap Posts Comments A Cell-Molecular Approach Predicts Vertebrate Evolution Compensating for deleterious mutations Jul 31st , 2011 by The Editors Fitness recovery and compensatory evolution in natural mutant lines of C . Elegans . By Estes S , Phillips PC , Denver DR . Evolution . 2011 Aug 65(8 2335-44. doi : 10.1111 j.1558-5646.2011.01276.x . Epub 2011 Apr 11. Abstract Deleterious mutation accumulation plays a central role in evolutionary genetics , conservation biology , human health , and evolutionary medicine e.g . methods of viral attenuation for live vaccines It is therefore important to understand whether and how quickly populations with accumulated deleterious mutational loads can recover fitness

  • A Cell-Molecular Approach Predicts Vertebrate Evolution

    Updated: 2011-07-30 15:08:08
    Home About People Resources Meetings courses The Evolution Medicine Review bridging the gap Posts Comments Autism and Acquired Misapprehensions about Heritability Compensating for deleterious mutations A Cell-Molecular Approach Predicts Vertebrate Evolution Jul 30th , 2011 by The Editors Mol Biol Evol 2011 doi : 10.1093 molbev msr134 First published online : May 18, 2011 By  John Steven Torday and  Virender Kumar Rehan Abstract In contrast to the conventional use of genes to determine the evolution of phenotypes , we have functionally integrated epithelial-mesenchymal interactions that have facilitated lung phylogeny and ontogeny in response to major geologic epochs . As such , this model reveals the underlying principles of lung physiology based on the evolutionary interactions between

  • Report in Nature Medicine on Evolution and Cancer Meeting

    Updated: 2011-07-09 12:58:44
    Home About People Resources Meetings courses The Evolution Medicine Review bridging the gap Posts Comments Evolutionary medicine symposium Autism and Acquired Misapprehensions about Heritability Report in Nature Medicine on Evolution and Cancer Meeting Jul 9th , 2011 by The Editors Forty years on from Nixon’s war , cancer research evolves’ by Nadia Drake  in Nature Medicine      doi:10.1038 nm0711-757  Not open access Published online   07 July 2011 Up a : tree Cancer researchers look to Darwin to improve tumor . therapies SAN FRANCISCO Ever since US president Richard Nixon declared war on cancer in 1971, scientists and physicians have launched a full-on offensive against the disease , seeking to cure cancer by eradicating the multiplying enemy cells . But , with few exceptions ,

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